Melanoma

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Alteration of the intestinal microflora after chemotherapy in dogs

Eligibility Requirements
• Your dog must have a confirmed diagnosis of melanoma and several tests to ensure his/her general health and to assess how advanced the disease is prior to treatment. The tumor will be biopsied prior to therapy. Tumors must be of a certain size (2-8 cm in the longest diameter) and your dog must have no other significant health problems. This study also includes dogs with only a single site as well as dogs with metastatic (spread of the tumor to other locations) disease.

Satraplatin for any tumor, including lymphoma

Eligibility Requirements
• Any tumor, including lymphoma confirmed by histopathology or cytology

Study Objective
To determine efficacy of using Satraplatin for various types of cancer using 5mg/m2 daily (orally).

Compensation
This study is partially funded. Please click on link for more details.

Canine patients with osteosarcoma, lymphoma, or oral malignant melanoma, mast cell tumors, soft tissue sarcomas/histiocytic sarcoma/malignant histiocytosis, primary pulmonary cancer, hemangiosarcomas

Eligibility Requirements
• Requirements vary for each type of cancer listed above. Please click on link for more details.

Study Objective
The goal of the CCOGC and UC Davis will be to populate the Pfizer-CCOGC Biospecimen Repository with diseased tissues and specific normal tissues from dogs with cancer over the next three years.

Compensation
This study is partially funded. Please click on link for more details.

Liposomal clodronate in canine cancer (excluding mast cell tumor, hemangiosarcoma and malignant histiocytosis)

Eligibility Requirements
• Dogs with biopsy-confirmed cancers (excluding mast cell tumor, hemangiosarcom and malignant histiocytosis) are potentially eligible
• The tumor must be less than 8cm (approximately 3.5 inches) in diameter and located in an easily accessible area for biopsy.
• Dogs must have good function of liver and kidneys and acceptable blood cell counts.
• Dogs must be free of underlying disease.

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